GeneDirector

The Optimal Solution for Microarray Data Management

GeneDirector 3.5 is the leading-edge comprehensive microarray data management solution. It is your central repository of ALL data associated with array experiments and is designed to organize, retrieve, analyze, and query all of your microarray data. GeneDirector 3.5 provides an end-to-end solution for the microarray workflow process, starting from sample management and tracking, through automated image analysis and results generation. Every step of the microarray experimental process is modeled and allows users to be fully MIAME compliant.

Multiple microarray platform support including cgh GeneDirector 3.5 is built on a proprietary architecture that allows for flexible workflows to be defined, yet still enforce Standard Operating Procedures and Protocols defined by your organization. And, as an enterprise-wide solution, this flexibility extends throughout your organization, fostering collaboration between your scientists and departments.

With support for major industry platforms, and automated batch import/export features, GeneDirector 3.5 simplifies operations and minimizes technician error. Built on an industrial strength Oracle database, you are assured of data integrity and security. And now, with the click of the mouse, you can rapidly publish and submit your data to the ArrayExpress public repository.

Results For Your Entire Enterprise

GeneDirector 3.5 provides features and benefits for every person who is involved in your microarray research program.

Comprehensive & Customizable Workflow - GeneDirector 3.5 evolves as your organization grows.

An end-to-end solution for every aspect of the microarray workflow (from biomaterials and arrays, through sample processing, hybridization, scanning and quantification)
Unique database architecture allows for very flexible workflow while providing enforcement of protocols and terminology ensuring consistency between experiments
On-Site configuration allows rapid customization and modifications without the need for expensive custom development
Add unlimited number of properties to any field in the database without custom programming
Properties can be any data type: numeric, text, image, or binary
Enforce submission of key properties
Enforce common vocabulary
Define unlimited number of study types and factors for your experiments

Secure Collaboration - comprehensive state-of-the-art protection for your data.

Based on Oracle comprehensive security infrastructure
Security change propagation and ownership transfer
Reader clients provide access to the database by anyone who has been provided with the permission and wants to retrieve data from GeneDirector
All or any part of the data can be shared with individuals or groups, for example:

Only quantifications
Quantifications and images
Images and sample information

Generation of Tab2MAGE file based on a GeneDirector project - allowing for easy submission to ArrayExpress data repository.
Multiple groups and administrators

Data Integrity - Offers the peace of mind and confidence that comes with a relational database solution.

User is able to review image analysis results directly from relationship viewer, providing mechanism for quick data QC.
Manage data associated with array experiments
Enables users to store and backup data from a secure and centralized repository
Scalable "industrial strength" Oracle database backend allowing for:

Enforcement of correct relationships among the data to ensure data integrity
Terabytes of data storage
Support hundreds of simultaneous users
Complex custom queries can be constructed to search for specific information (e.g., expression signatures) across the entire database

Supports MIAME industry standards
Customize security settings to fit he needs of your users and projects
Link Bioanalyzer data directly to RNA and amplified RNA data

Advanced Automation - Let GeneDirector do the work for you, minimizing user error while improving efficiency.

Simple batch import/export operation simplifies operation
New Single-Button project submission to public repository (ArrayExpress)
Improve performance by allowing users to multi-task
Ensure consistency, minimize error among data through batch processes
Batch import of Sample Information, Quantified Arrays, Scanned Arrays, Agilent Feature Extraction Files, RMA, Illumina BeadStudio and dChip data
Batch export native Affymetrix files
Batch create sets of arrays, process multiple images, pre-process (normalize) data sets
Improve productivity, efficiency, and quality of results
Batch import ImaGene data and automatically establish data relationships
Automated Pre-Processing/Data Cleansing
Robust, unsupervised, image processing for high-throughput environments

Platform Independence & Compatibility

Direct integration with all commercial array hardware platforms - Affymetrix, Agilent, Axon, PerkinElmer, Applied Precision, Genomic Solutions, and more
Open architecture allows for integration with common equipment and software tools

Agilent Bioanalyzer for RNA and aRNA data
Directly import QC data from Tecan automated hybridization station
Directly import data from Affymetrix GCOS software
Directly import images and process from Agilent, Axon, and many other scanners
Directly import quantifications generated by Agilent, Affymetrix, RMA, and many others

Java API provided for customer's own development and integration
Operating system independent - can run on Windows, Mac, and Linux
Supports MIAME compliant data model for sharing and publishing data

Rapid & Dynamic Search Capability

Quickly and simply find any data through use of data organization, search, or linked association
Project Summary can be reviewed, drill down and edit as required
Comprehensive Search tool
Keyword, General and Custom Query capability
Relationship viewer - allows user to find information based on inherent relationships between array design, array type and samples, and experiment data
Limit search scope by owner, project, date range, or data type

Full Affymetrix Support

Import from Affymetrix GeneChip Operating System (GCOS)
One Button import of all native Affymetrix files
Store both raw data as well as processed quantifications

Raw data can be retrieved and reprocessed
Processed data can be used for analysis and mining

Enterprise Collaboration Capability -

Secure access allows individuals and groups to collaborate
Project owner can assign work to various work groups
Owner has full access
Users can belong to more than one group within the system
Flexibility in assigning projects

Array Results Manager for GeneDirector

The first tool that turns enterprise-wide microarray results into knowledge.

Multi-platform support for results generated by any algorithm, software, and array type
Support for multi-disciplinary teams - lab technicians, bioinformatics / biostatistics, and researchers
Simplified analysis, with reliable and reproducible results, with a single mouse click
Centralized storage, management, retrieval, integration, and visualization of microarray results
Scalable enterprise solution with c entralized and comprehensive database.
Structured data preparation and analysis workflow via protocols
Enterprise annotation server provides queries across multiple array platforms

To request further information about the Array Results Manager - CLICK HERE.

System Requirements

Platforms Supported: Windows Win2k/WinXP/Vista, Linux, Mac OS X
Database Supported: Oracle 10g
Minimum: Pentium 4 or G4 1.0 GHz, 512MB RAM, 150 MB HD
Recommended: Xeon or G5 2+ GHz, 2 GB RAM, 500 MB HD